Previous legislation required all medications containing botulinum toxin to be tested on mice for quality assurance. However, in November 2011, Swissmedic was the first European regulatory authority to approve a test method that does not involve animal testing. A few months later, the European Medicines Agency (EMA) also approved this test method. Since June 2012, it is possible to supply botulinum products in Switzerland that have not involved animal testing. Smoothline now only uses products that have not required testing on animals.